|
KMID : 0931320210210020156
|
|
대한상부위장관.헬리코박터학회지
2021 Volume.21 No. 2 p.156 ~ p.160
|
|
|
C-kit-negative Extragastrointestinal Stromal Tumor Originating in the Mesentery Misdiagnosed as an Ovarian Tumor before Surgery
|
|
Lim Jong-Ryeul
Baeg Myong-Ki
Ahn Sang-Jeong
Ha Man-Ho
Ko Sun-Hye
Kwon Hyuk-I
Han Jae-Ho
|
|
|
Abstract
|
|
|
|
Gastrointestinal stromal tumors (GISTs) are rare digestive system malignancies with extragastrointestinal stromal tumors (EGISTs) being even less. Diagnosing GISTs usually requires the identification of c-kit (CD117) expression by immunohistochemical staining. A 53-year-old woman complaining of dyspepsia was referred for the evaluation of a 1.5-cm extrinsic compression at the greater curvature of the proximal antrum. EUS revealed a multiseptated mass with positive Doppler findings. Abdominal CT showed that she harbored a large, 20-cm mass in her abdominal cavity, most likely arising from the right ovary. Surgery revealed a hypervascular tumor arising from the mesentery and attached to the gastric lesser curvature. Pathological examination revealed negativity for c-kit, but positivity for the protein “Discovered on GIST-1” (DOG1), confirming the EGIST diagnosis. Herein, we report this rare case of a c-kit-negative EGIST originating in the mesentery, which was diagnosed based on staining for DOG1.
|
|
|
KEYWORD
|
|
|
C-kit protein, DOG-1 protein, Gastrointestinal stromal tumor, Mesentery
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|